diff --git a/rust.spec b/rust.spec
index 06059be..7c8da03 100644
--- a/rust.spec
+++ b/rust.spec
@@ -898,6 +898,9 @@ test -r "%{profiler}"
 # Skipping PGO on s390x until we get LLVM 20, due to
 # https://github.com/llvm/llvm-project/issues/124001
 %ifnarch s390x
+# rustc is exibiting signs of miscompilation on pwr9+pgo (root cause TBD),
+# so we're skipping pgo on rhel ppc64le for now.
+%if !( 0%{?rhel} && "%{_target_cpu}" == "ppc64le" )
 %if %with rustc_pgo
 # Build the compiler with profile instrumentation
 %define profraw $PWD/build/profiles
@@ -914,6 +917,7 @@ rm -r "%{profraw}" build/%{rust_triple}/stage2*/
 %global __x %{__x} --rust-profile-use="%{profdata}"
 %endif
 %endif
+%endif
 
 # Build the compiler normally (with or without PGO)
 %{__x} build sysroot