diff -urNp a/snmplib/transports/snmpUDPBaseDomain.c b/snmplib/transports/snmpUDPBaseDomain.c
--- a/snmplib/transports/snmpUDPBaseDomain.c	2023-08-01 08:20:56.776099134 +0200
+++ b/snmplib/transports/snmpUDPBaseDomain.c	2023-08-01 08:23:18.921323874 +0200
@@ -293,7 +293,7 @@ int netsnmp_udpbase_sendto(int fd, const
         }
 
         rc = sendmsg(fd, &m, MSG_NOSIGNAL|MSG_DONTWAIT);
-        if (rc >= 0 || errno != EINVAL)
+        if (rc >= 0 || (errno != EINVAL && errno != ENETUNREACH))
             return rc;
 
         /*