diff -Naur libwebp-0.4.0.orig/examples/tiffdec.c libwebp-0.4.0/examples/tiffdec.c
--- libwebp-0.4.0.orig/examples/tiffdec.c	2013-12-20 09:48:07.000000000 +0100
+++ libwebp-0.4.0/examples/tiffdec.c	2014-04-08 17:30:24.406858688 +0200
@@ -97,7 +97,7 @@
       pic->width = width;
       pic->height = height;
       // TIFF data is ABGR
-#ifdef __BIG_ENDIAN__
+#if (__BYTE_ORDER__ == __ORDER_BIG_ENDIAN__)
       TIFFSwabArrayOfLong(raster, width * height);
 #endif
       pic->use_argb = 1;
diff -Naur libwebp-0.4.0.orig/src/dsp/lossless.c libwebp-0.4.0/src/dsp/lossless.c
--- libwebp-0.4.0.orig/src/dsp/lossless.c	2013-12-20 09:48:07.000000000 +0100
+++ libwebp-0.4.0/src/dsp/lossless.c	2014-04-08 17:32:09.608802898 +0200
@@ -1293,7 +1293,7 @@
     while (src < src_end) {
       uint32_t argb = *src++;
 
-#if !defined(__BIG_ENDIAN__)
+#if (__BYTE_ORDER__ == __ORDER_LITTLE_ENDIAN__)
 #if !defined(WEBP_REFERENCE_IMPLEMENTATION)
 #if defined(__i386__) || defined(__x86_64__)
       __asm__ volatile("bswap %0" : "=r"(argb) : "0"(argb));
@@ -1313,7 +1313,7 @@
       dst[2] = (argb >>  8) & 0xff;
       dst[3] = (argb >>  0) & 0xff;
 #endif
-#else  // __BIG_ENDIAN__
+#else  // __BYTE_ORDER__ == __ORDER_BIG_ENDIAN__
       dst[0] = (argb >>  0) & 0xff;
       dst[1] = (argb >>  8) & 0xff;
       dst[2] = (argb >> 16) & 0xff;
diff -Naur libwebp-0.4.0.orig/src/utils/bit_reader.h libwebp-0.4.0/src/utils/bit_reader.h
--- libwebp-0.4.0.orig/src/utils/bit_reader.h	2013-12-20 09:48:07.000000000 +0100
+++ libwebp-0.4.0/src/utils/bit_reader.h	2014-04-08 17:34:14.600924510 +0200
@@ -156,7 +156,7 @@
     bit_t bits;
     const lbit_t in_bits = *(const lbit_t*)br->buf_;
     br->buf_ += (BITS) >> 3;
-#if !defined(__BIG_ENDIAN__)
+#if (__BYTE_ORDER__ == __ORDER_LITTLE_ENDIAN__)
 #if (BITS > 32)
 // gcc 4.3 has builtin functions for swap32/swap64
 #if defined(__GNUC__) && \
@@ -196,7 +196,7 @@
 #else   // BITS == 8
     bits = (bit_t)in_bits;
 #endif
-#else    // BIG_ENDIAN
+#else    // __BYTE_ORDER__ == __ORDER_BIG_ENDIAN__
     bits = (bit_t)in_bits;
     if (BITS != 8 * sizeof(bit_t)) bits >>= (8 * sizeof(bit_t) - BITS);
 #endif
diff -Naur libwebp-0.4.0.orig/src/utils/bit_writer.c libwebp-0.4.0/src/utils/bit_writer.c
--- libwebp-0.4.0.orig/src/utils/bit_writer.c	2013-12-20 09:48:07.000000000 +0100
+++ libwebp-0.4.0/src/utils/bit_writer.c	2014-04-08 17:34:35.161108984 +0200
@@ -237,7 +237,7 @@
 
 void VP8LWriteBits(VP8LBitWriter* const bw, int n_bits, uint32_t bits) {
   if (n_bits < 1) return;
-#if !defined(__BIG_ENDIAN__)
+#if (__BYTE_ORDER__ == __ORDER_LITTLE_ENDIAN__)
   // Technically, this branch of the code can write up to 25 bits at a time,
   // but in prefix encoding, the maximum number of bits written is 18 at a time.
   {
@@ -247,7 +247,7 @@
     *(uint32_t*)p = v;
     bw->bit_pos_ += n_bits;
   }
-#else  // BIG_ENDIAN
+#else  // __BYTE_ORDER__ == __ORDER_BIG_ENDIAN__
   {
     uint8_t* p = &bw->buf_[bw->bit_pos_ >> 3];
     const int bits_reserved_in_first_byte = bw->bit_pos_ & 7;