diff --git a/.gitignore b/.gitignore
index 1fcb73d..b46ca2f 100644
--- a/.gitignore
+++ b/.gitignore
@@ -23,3 +23,4 @@
 /gtk-4.2.0.tar.xz
 /gtk-4.2.1.tar.xz
 /gtk-4.4.0.tar.xz
+/gtk-4.5.0.tar.xz
diff --git a/0001-build-Fix-detection-for-pre-compiled-css-files.patch b/0001-build-Fix-detection-for-pre-compiled-css-files.patch
deleted file mode 100644
index 1292e85..0000000
--- a/0001-build-Fix-detection-for-pre-compiled-css-files.patch
+++ /dev/null
@@ -1,29 +0,0 @@
-From 552a4b2c82f41c1dbba410b825673cf67d089b68 Mon Sep 17 00:00:00 2001
-From: Kalev Lember <klember@redhat.com>
-Date: Mon, 23 Aug 2021 15:38:46 +0200
-Subject: [PATCH] build: Fix detection for pre-compiled css files
-
-The default theme changed from Adwaita to Default and this tripped up
-the logic to detect if the tarball builds contain pre-built css files or
-not. Fix this by looking at pre-compiled css files in themes/Default/
-instead of themes/Adwaita/.
----
- gtk/meson.build | 2 +-
- 1 file changed, 1 insertion(+), 1 deletion(-)
-
-diff --git a/gtk/meson.build b/gtk/meson.build
-index fa66764c50..bfb5105fe5 100644
---- a/gtk/meson.build
-+++ b/gtk/meson.build
-@@ -842,7 +842,7 @@ gtk_gresources_xml = configure_file(output: 'gtk.gresources.xml',
- 
- theme_deps = []
- # For git checkouts, but not for tarballs...
--if not fs.exists('theme/Adwaita/Adwaita.css')
-+if not fs.exists('theme/Default/Default-light.css')
-   # ... build the theme files
-   sassc = find_program('sassc', required: false)
-   if not sassc.found()
--- 
-2.31.1
-
diff --git a/gtk4.spec b/gtk4.spec
index 8372234..9496ae5 100644
--- a/gtk4.spec
+++ b/gtk4.spec
@@ -3,7 +3,7 @@
 %endif
 
 %global glib2_version 2.66.0
-%global pango_version 1.47.0
+%global pango_version 1.49.1
 %global cairo_version 1.14.0
 %global gdk_pixbuf_version 2.30.0
 %global wayland_protocols_version 1.21
@@ -16,15 +16,13 @@
 %global __provides_exclude_from ^%{_libdir}/gtk-4.0
 
 Name:           gtk4
-Version:        4.4.0
-Release:        4%{?dist}
+Version:        4.5.0
+Release:        1%{?dist}
 Summary:        GTK graphical user interface library
 
 License:        LGPLv2+
 URL:            https://www.gtk.org
-Source0:        https://download.gnome.org/sources/gtk/4.4/gtk-%{version}.tar.xz
-# Backported from upstream
-Patch0:         0001-build-Fix-detection-for-pre-compiled-css-files.patch
+Source0:        https://download.gnome.org/sources/gtk/4.5/gtk-%{version}.tar.xz
 
 BuildRequires:  cups-devel
 BuildRequires:  desktop-file-utils
@@ -46,6 +44,9 @@ BuildRequires:  pkgconfig(gobject-introspection-1.0)
 BuildRequires:  pkgconfig(graphene-gobject-1.0)
 BuildRequires:  pkgconfig(gstreamer-player-1.0)
 BuildRequires:  pkgconfig(json-glib-1.0)
+BuildRequires:  pkgconfig(libjpeg)
+BuildRequires:  pkgconfig(libpng)
+BuildRequires:  pkgconfig(libtiff-4)
 BuildRequires:  pkgconfig(pango) >= %{pango_version}
 BuildRequires:  pkgconfig(rest-0.7)
 BuildRequires:  pkgconfig(sysprof-4)
@@ -64,7 +65,7 @@ BuildRequires:  pkgconfig(xinerama)
 BuildRequires:  pkgconfig(xkbcommon)
 BuildRequires:  pkgconfig(xrandr)
 BuildRequires:  pkgconfig(xrender)
-BuildRequires:  /usr/bin/xsltproc
+BuildRequires:  /usr/bin/rst2man
 
 # standard icons
 Requires: adwaita-icon-theme
@@ -226,6 +227,9 @@ desktop-file-validate %{buildroot}%{_datadir}/applications/*.desktop
 %{_mandir}/man1/gtk4-widget-factory.1*
 
 %changelog
+* Mon Nov 01 2021 Kalev Lember <klember@redhat.com> - 4.5.0-1
+- Update to 4.5.0
+
 * Mon Sep 27 2021 Kalev Lember <klember@redhat.com> - 4.4.0-4
 - Build with tracker support enabled (#1908874)
 
diff --git a/sources b/sources
index cf4673d..9357efc 100644
--- a/sources
+++ b/sources
@@ -1 +1 @@
-SHA512 (gtk-4.4.0.tar.xz) = de0b6508df3fa4523a7e54cf417ac31292c833346409ff89fd4daf886edad16ffe60b6ed77a85451bd36b96098c8437d56c6fd42daca33c52db8dc57a25753b6
+SHA512 (gtk-4.5.0.tar.xz) = 07b776a0a0b96cb257e6788c1c9eafbd4f16e688f455a4255abf240fa693c1506c49d78e4ca50bd2eeab0474b8b065673dc96f4bf8d0fe50792a1ac1bcbcceae