diff --git a/grubby-bls b/grubby-bls
index fc50e67..59df26e 100755
--- a/grubby-bls
+++ b/grubby-bls
@@ -595,23 +595,29 @@ remove_var_prefix() {
 
 update_grubcfg()
 {
-    # Older ppc64le OPAL firmware don't have BLS support so grub2-mkconfig has to be run
-    # to generate a config with menuentry commands.
-    if [ "${arch}" = "ppc64le" ] && [ -d /sys/firmware/opal ]; then
+    # Turn on RUN_MKCONFIG on different archs/scenarios
+    if [[ "${arch}" = 's390' ]] || [[ "${arch}" = 's390x' ]]; then
+        # On s390/s390x systems, run mkconfig/zipl
         RUN_MKCONFIG="true"
-    fi
-
-    # PV and PVH Xen DomU guests boot with pygrub that doesn't have BLS support,
-    # also Xen Dom0 use the menuentries from 20_linux_xen and not the ones from
-    # 10_linux. So grub2-mkconfig has to run for both Xen Dom0 and DomU.
-    if [[ -e /sys/hypervisor/type ]] && grep -q "^xen$" /sys/hypervisor/type; then
+    elif [[ "${arch}" = "ppc64le" ]] && [[ -d /sys/firmware/opal ]]; then
+        # Older ppc64le OPAL firmware don't have BLS support so grub2-mkconfig has to be run
+        # to generate a config with menuentry commands.
+        RUN_MKCONFIG="true"
+    elif [[ -e /sys/hypervisor/type ]] && grep -q "^xen$" /sys/hypervisor/type; then
         if [ ! -e /sys/hypervisor/guest_type ] || ! grep -q "^HVM$" /sys/hypervisor/guest_type; then
+            # PV and PVH Xen DomU guests boot with pygrub that doesn't have BLS support,
+            # also Xen Dom0 use the menuentries from 20_linux_xen and not the ones from
+            # 10_linux. So grub2-mkconfig has to run for both Xen Dom0 and DomU.
             RUN_MKCONFIG=true
         fi
     fi
 
     if [[ $RUN_MKCONFIG = "true" ]]; then
-        grub2-mkconfig --no-grubenv-update -o "${grub_config}" >& /dev/null
+        if [[ $bootloader = "zipl" ]]; then
+            zipl
+        else
+            grub2-mkconfig --no-grubenv-update -o "${grub_config}" &> /dev/null
+        fi
     fi
 }
 
diff --git a/grubby.spec b/grubby.spec
index d4ab5df..b8021a4 100644
--- a/grubby.spec
+++ b/grubby.spec
@@ -1,6 +1,6 @@
 Name: grubby
 Version: 8.40
-Release: 68%{?dist}
+Release: 69%{?dist}
 Summary: Command line tool for updating bootloader configs
 License: GPLv2+
 URL: https://github.com/rhinstaller/grubby
@@ -131,6 +131,10 @@ current boot environment.
 %{_mandir}/man8/*.8*
 
 %changelog
+* Wed Sep 03 2025 Leo Sandoval <lsandova@redhat.com> - 8.40-69
+- grubby-bls: in s390* systems, run zipl on grub cfg update event
+  Resolves: #RHEL-106612
+
 * Wed Jul 30 2025 Leo Sandoval <lsandova@redhat.com> - 8.40-68
 - Update cfg when setting a default kernel
   Resolves: #RHEL-106612